The Relationship between Absolute Neutrophil Count and Erythrocyte Index in Hyperuricemia Patients

Meri Meri, Noval Pahrul Nurhidayat

Abstract


ABSTRACT

 

Hyperuricemia is a condition of a person with uric acid levels in the blood that exceed normal values. Increased uric acid can be detrimental because it is considered as damage-associated molecular pattern molecules (DAMPs), causing an immune response and detrimental to health. However, uric acid can act as an antioxidant in the body. Uric acid can protect the quality of erythrocytes. However, erythrocytes can suffer damage due to oxidative stress as a result of the inflammatory process. An increase in the absolute neutrophil count is an indication of inflammation. The aim of this study is to determine the relationship between absolute neutrophil count and erythrocyte index in hyperuricemia. Sampling was done by purposive sampling with the criteria of males aged 18-65 years, not obese, hyperuricemia, and fasting. The sample used was venous blood, then examined using a haematology analyzer at Jasa Kartini Hospital, Tasikmalaya. The results of the study of 30 respondents showed that the average uric acid was 8.863 mg / dl. Based on statistical tests using the Spearman correlation test, it showed that there was no significant relationship between the absolute number of neutrophils and the erythrocyte index, which was indicated by P> 0.05. The conclusion is that hyperuricemia with a mean of 8.863 mg / dl did not show any relationship between the absolute neutrophil count and the erythrocyte index.

 

Keywords: Hyperuricemia, absolute neutrophil count, erythrocyte index.


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