DIFFERENCES IN VITAMIN C LEVELS IN NORMAL PREGNANCY WITH THE INCIDENCE OF ABORTION

Abstract

ABSTRACT

The incidence of abortion is still high in the world and in Indonesia. In obstetric care, abortion is still a problem and is a cause of increased mortality, maternal and neonatal morbidity. One of the causes of abortion is the imbalance of antioxidants that occurs during placentation. This study aims to determine the differences in vitamin C levels in normal pregnancy and the incidence of abortion. The research design was cross sectional. This research was conducted at RS Bayangkara Padang, RS dr. Reksodiwiryo Padang, Ibu Sina Padang Hospital, dr. Rasidin Padang, Puskesmas Andalas, Biomedical Labor and Biochemistry Labor, Faculty of Medicine, University of Andalas, in December 2016-February 2018. The sample of this study was 14 pregnant women diagnosed with abortion and 14 normal pregnant women ≤ 20 weeks using the conseticutuve technique. sampling. Vitamin C levels were checked by the ELISA method. This study showed that the mean vitamin C levels were 30.78 ± 5.26 µmol / L in abortion with p value ˃ 0.05. In this study, there was a tendency for the role of vitamin C levels in the incidence of abortion and normal pregnancy, but it was not statistically significant. It is recommended that before checking vitamin C levels, an assessment of the consumption of food sources of vitamin C and vitamin C supplements should be carried out. Perform routine ANC examinations from Trimester I to Trimester III to be able to prevent early abortion that threatens

Keywords: Vitamin C, Abortion, Normal Pregnancy.