Nursilri meidania, Dea Selvia, Rodiani -


Coronavirus Disease 2019 (COVID-19) is a new disease that has never been identified in humans before. The type of virus is a single-strain RNA with a particle size of 120-160 nm. The coronavirus that caused a pandemic was first reported in Wuhan, China on December 31, 2019, is a new type of SARS-CoV 2 and has a genome sequence similar to SARS-CoV and MERS-CoV. This virus is dangerous and has caused deaths recorded as many as 532,340 in the world and 3,241 deaths in Indonesia on July 6, 2020. Pregnant women are included in the group that is vulnerable to infection. COVID-19 infection can cause various symptoms ranging from mild, moderate and severe. The main clinical symptoms that can appear are fever (temperature> 38 ° C), cough and difficulty breathing. These complaints can be accompanied by the presence of severe tightness, fatigue, myalgia, gastrointestinal symptoms such as diarrhea and other respiratory symptoms. The principles that must be considered in managing COVID 19 in pregnancy are early separation, aggressive infection control methods, testing for COVID 19 and other common infection tests, oxygen therapy if necessary, monitoring of fluid therapy,monitoring of the fetus and uterine contractions, mechanical ventilation associated with progressive respiratory symptoms, delivery planning and a team-based approach with multidisciplinary consultation

Full Text:



Khan S, Peng L, Siddique R et al. Impact of COVID-19 infection on pregnancy outcomes and the risk of maternal-to-neonatal intrapartum transmission of COVID-19 during natural birth. Infect Control Hosp Epidemiol. 2020; 41 (6): 748–750.

P.I. Lee, P.R. Hsueh, Emerging threats from zoonotic coronaviruses-from SARS and MERS to 2019-nCoV, J. Microbiol. Immunol. Infect. (2020), 10.1016/j.jmii.2020.02.001.

Pedoman Pencegahan Dan Pengendalian Coronavirus Disease (COVID-19). Direktorat Jenderal Pencegahan dan Pengendalian Penyakit. Kementerian Kesehatan RI. 2020.

World Health Organization. 2020. Diakses pada 08 Juli 2020

Qiao J. What are the risks of COVID-19 infection in pregnant women? Lancet. 2020;395(10226):760-2.

Yang H, Wang C, Poon LC. Novel coronavirus infection and pregnancy. Ultrasound Obstet Gynecol. 2020.

C. Wolthers, P.M. Wertheim-van Dillen, J. Kaandorp, J. Spaargaren, B. Berkhout. Identification of a new human coronavirus, Nat. Med. 10 (4):368–373.

Yu N, Li W, Kang Q et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: A retrospective, single-Centre, descriptive study. Lancet Infect Dis 2020; 20: 559–564.

Rekomendasi Penanganan Infeksi Virus Corona (COVID-19). 2020. Perkumpulan Obstetri dan Ginekologi Indonesia.

Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The reproductive number of COVID-19 is higher compared to SARS coronavirus. J Travel Med. 2020; 27(2).

Wan Y, Shang J, Graham R, Baris RS, Li F. Receptor recognition by novel coronavirus from Wuhan: An analysis based on decadelong structural studies of SARS. J. Virol. American Society for Microbiology: 2020. p 1-24.

Perhimpunan Dokter Paru Indonesia. Panduan Praktik Klinis: Pneumonia 2019-nCoV. PDPI: Jakarta; 2020.

World Health Organization. Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected. interim guidance.

Wang Z, Qiang W, Ke H. A Handbook of 2019-nCoV Pneumonia Control and Prevention. Hubei Science and Technologi Press. China; 2020

Ferrazzi EM, Frigerio L, Cetin I et al. COVID-19 obstetrics task force, Lombardy, Italy: Executive management summary and short report of outcome. Int J Gynaecol Obstet. 2020b; 149 (3): 377-378

Zhang H, Penninger JM, Li Y, Zhong N, Slutsky AS. Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive Care Med. 2020; published online March 3. DOI: 10.1007/s00134-020- 05985-9

Asadi L, Razieh ST, Hadiseh SN, Maryam M. New corona virus (COVID-19) management in pregnancy and childbirth. Arch Clin Infect Dis. 2020 ; 1-13

L. Van der Hoek, K. Pyrc, M.F. Jebbink, W. Vermeulen-Oost, R.J. Berkhout, K. Li G, Fan Y, Lai Y, Han T, Li Z, Zhou P, et al. Coronavirus infections and immune responses. J Med Virol. 2020; 92(4):424-32.

Li X, Geng M, Peng Y, Meng L, Lu S. Molecular immune pathogenesis and diagnosis of COVID-19. J Pharm Anal. 2020; published online March 5. DOI: 10.1016/j.jpha.2020.03.001

Qin C, Zhou L, Hu Z, Zhang S, Yang S, Tao Y, et al. Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. 2020; published online March 12.

Dashraath P, Wong JLJ, Lim MXK et al. Coronavirus disease2019 (COVID-19) pandemic and pregnancy. Am J ObstetGynecol. 2020

Di Mascio D, Khalil A, Saccone G et al. Outcome of Corona virus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2020

Breslin N, Baptiste C, Gyamfi-Bannerman C et al. COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals. Am J Obstet Gynecol MFM. 2020

Wu X, Sun R, Chen J, Xie Y, Zhang S, Wang X. Radiological findings and clinical characteristics of pregnant women with COVID-19 pneumonia. Int J Gynaecol Obstet 2020

Zhao X, dkk. Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening. European Journal of Clinical Microbiology & Infectious Diseases. 2020; 1- 12.

Baud D, Greub G, Favre G et al. Second-trimester miscarriage in a pregnant woman with SARS-CoV-2 infection.

RCOG. Coronavirus (COVID-19) infection in pregnancy information for healthcare professionals Version 8 2020.

Liang H dan Ganesh A. Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow?. Acta Obstet Gynaecol Scand. 2020; 415-26.

Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The reproductive number of COVID-19 is higher compared to SARS coronavirus. J Travel Med. 2020;27(2).

Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019- nCoV pneumonia. Transl Pediatr. 2020; 9: 51-60



  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Jurnal Kesehatan Saintika Meditory
Published by Stikes Syedza Saintika Padang 

Pusat Penelitian dan Pengabdian Masyarakat, STIKes SYEDZA Saintika Padang

Jl. Prof. Dr. Hamka No. 228 Air Tawar Timur Padang - Sumatera Barat

Phone: 082384992512


View My Stats